2′-Hydroxychalcone-1, CAS 1214-47-7

Product Description: 2′-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells[1]. 2′-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp[2].

Applications: COVID-19-immunoregulation

Formula: C15H12O2

References: [1]Kaila P Medina-Alarcón, et al. Antifungal activity of 2'-hydroxychalcone loaded in nanoemulsion against Paracoccidioides spp. Future Microbiol. 2020 Jan:15:21-33. /[2]Xiao Wang, et al. 2'-Hydroxychalcone Induces Autophagy and Apoptosis in Breast Cancer Cells via the Inhibition of the NF-κB Signaling Pathway: In Vitro and In Vivo Studies. Nutrients. 2024 Feb 13;16(4):514.

CAS Number: 1214-47-7

Molecular Weight: 224.25

Compound Purity: 96.76

Research Area: Cancer; Infection

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;Fungal;NF-κB

• SKU: MEXHY-W012349-500
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W012349-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK