2-Iminobiotin, CAS 13395-35-2

Product Description: 2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].

Applications: Neuroscience-Neuromodulation

Formula: C10H17N3O2S

References: [1]Sup SJ, et al. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun. 1994 Oct 28;204(2):962-8./[2]Zitta K, et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study. Front Pharmacol. 2018 Jan 11;8:971.

CAS Number: 13395-35-2

Molecular Weight: 243.33

Compound Purity: 98.0

Research Area: Neurological Disease

Solubility: DMSO : 12.5 mg/mL (ultrasonic)

Target: NO Synthase

• SKU: MEXHY-118700-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-118700-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK