20S Proteasome-IN-5

Product Description: 20S Proteasome-IN-5 (Compound 5) is a macrocyclic inhibitor of the 20S Proteasome, with IC50 values of 0.19 and 52.5 μM for ChT-L and PGPH-L activity, respectively[1].

Formula: C37H46N6O10

References: [1]Götz MG, et al. Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. ACS Med Chem Lett. 2024 Mar 27;15(4):533-539.

Molecular Weight: 734.80

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Proteasome

• SKU: MEXHY-158150-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158150-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK