Product Description: 3-Methylxanthine (Standard) is the analytical standard of 3-Methylxanthine. This product is intended for research and analytical applications. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.
Formula: C6H6N4O2
References: [1]Tanaka H, et al. Inhibition of cyclic GMP phosphodiesterase by xanthine derivatives relaxes guinea-pig trachealis smooth muscle. Clin Exp Pharmacol Physiol. 1991 Mar;18(3):163-8./[2]Yamamoto K, et al. Neurotoxic convulsions induced by theophylline and its metabolites in mice. Biol Pharm Bull. 1996 Jun;19(6):869-72.
CAS Number: 1076-22-8
Molecular Weight: 166.14
Research Area: Others
Solubility: 10 mM in DMSO/1M NaOH : 50 mg/mL (ultrasonic;adjust pH to 11 with 1M NaOH)/DMF : < 1 mg/mL/DMSO : 2.61 mg/mL (ultrasonic)/Ethanol : < 1 mg/mL/H2O : < 0.1 mg/mL
Target: Endogenous Metabolite
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