4F-DDC

Product Description: 4F-DDC is a novel PARP1 inhibitor with an IC50 value of 82 nM. 4F-DDC induces DNA damage and activates the cGAS–STING pathway. 4F-DDC inhibits the growth of HCC-1937-derived tumor xenografts[1].

Formula: C16H14Br2FN3O2S

References: [1]Yonglong Jin, et al. A Novel Inhibitor of Poly(ADP- R ibose) Polymerase-1 Inhibits Proliferation of a BRCA-Deficient Breast Cancer Cell Line via the DNA D amage- A ctivated cGAS-STING Pathway. Chem Res Toxicol. 2024, 37, 4.

Molecular Weight: 491.17

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PARP

• SKU: MEXHY-163461-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163461-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK