6-Hydroxypyridin-2(1H)-one hydrochloride, CAS 10357-84-3

Description: 6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising biochemical modulator to reduce 5-fluorouracil (5-FU) toxicity without impairing its antitumor activity.

CAS Number: 10357-84-3

Formula: C5H6ClNO2

Molecular Weight: 147,56

References: Renck D, et al. Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity. J Med Chem. 2013 Nov 14;56(21):8892-902.

• SKU: TGMT4720-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T4720-1mL
• Green Labware: No
• Package Unit: 1 mL
• Quantity Unit: STK