6FC-GABA-Taxol

6FC-GABA-Taxol
SKU
MEXHY-D2341-0
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Manufacturer
MedChemExpress

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Product Description: 6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors[1].

Formula: C61H61FN2O19

References: [1]Rane D, et al. Synthesis of Monofluorinated 7-Hydroxycoumarin-3-Carboxamides as Cell-Permeable Fluorescent Molecular Probes. ACS Med Chem Lett. 2024;15(5):677-683. Published 2024 Apr 15.

Molecular Weight: 1145.14

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others
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SKU MEXHY-D2341-0
Manufacturer MedChemExpress
Manufacturer SKU HY-D2341-0
Green Labware No
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