A 83-01, CAS 909910-43-6

Description: A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures.

CAS Number: 909910-43-6

Formula: C25H19N5S

Molecular Weight: 421,52

References: Tojo M, et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 2005 Nov;96(11):791-800.

• SKU: TGMT3031-100mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T3031-100mg
• Package Unit: 100 mg
• Quantity Unit: STK