α-Amylase/α-Glucosidase-IN-11

Product Description: α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C33H40ClN5O5

References: [1]Ghannay S, et al. dentification of dual-target isoxazolidine-isatin hybrids with antidiabetic potential: Design, synthesis, in vitro and multiscale molecular modeling approaches. Heliyon. 2024 Feb 11;10(4):e25911.

Molecular Weight: 622.15

Research Area: Endocrinology

Solubility: 10 mM in DMSO

Target: Amylases;Glucosidase

• SKU: MEXHY-162390-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162390-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK