Aβ42 agonist-1, CAS 50635-12-6

Product Description: Aβ42 agonist-1 (compound 7a) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-1 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-1 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells[1].

Formula: C15H11NO2

References: [1]Zhao Y et al. Small Molecules N-Phenylbenzofuran-2-carboxamide and N-Phenylbenzo[b]thiophene-2-carboxamide Promote Beta-Amyloid (Aβ42) Aggregation and Mitigate Neurotoxicity. ACS Chem Neurosci. 2023 Nov 16.

CAS Number: 50635-12-6

Molecular Weight: 237.25

Compound Purity: 99.90

Research Area: Neurological Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Amyloid-β

• SKU: MEXHY-149763-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-149763-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK