Product Description: AChE/BChE-IN-19 (Compound 12) is a nicotinic hydrazide derivative. AChE/BChE-IN-19 is a inhibitor of AChE (IC50 = 21.45 nM) and BChE (IC50 =18.42 nM). AChE/BChE-IN-19 can be used in Alzheimer's disease research[1].
Applications: Neuroscience-Neurodegeneration
Formula: C26H22N4O3
References: [1]Resiţ Çakmak, et al. Synthesis of Novel Hydrazide−Hydrazone Compounds and In Vitro and In Silico Investigation of Their Biological Activities against AChE, BChE, and hCA I and II. ACS Omega. 2024, 9, 18, 20030–20041
Molecular Weight: 438.48
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Cholinesterase (ChE)