Adavosertib, CAS 955365-80-7

Description: Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.

CAS Number: 955365-80-7

Formula: C27H32N8O2

Molecular Weight: 500,6

References: Hirai H, et al. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. Mol Cancer Ther. 2009 Nov;8(11):2992-3000.

• SKU: TGMT2077-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T2077-1mL
• Package Unit: 1 mL
• Quantity Unit: STK