Adezmapimod, CAS 152121-47-6

Description: Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive. Adezmapimod possesses autophagy and mitochondrial autophagy activating activity. Adezmapimod displays more than 100-fold higher selectivity than PKB, LCK, and GSK-3β.

CAS Number: 152121-47-6

Formula: C21H16FN3OS

Molecular Weight: 377,43

References: Henklova P, et al. SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes. Eur J Pharmacol. 2008 Sep 28;593(1-3):16-23.

• SKU: TGMT1764-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T1764-1mL
• Package Unit: 1 mL
• Quantity Unit: STK