Afatinib, CAS 850140-72-6

Description: Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).

CAS Number: 850140-72-6

Formula: C24H25ClFN5O3

Molecular Weight: 485,94

References: Wong CH, et al. Preclinical evaluation of afatinib (BIBW2992) in esophageal squamous cell carcinoma (ESCC). Am J Cancer Res. 2015 Nov 15;5(12):3588-99.

• SKU: TGMT21312-200mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T21312-200mg
• Package Unit: 200 mg
• Quantity Unit: STK