Aldose reductase-IN-7

Product Description: Aldose reductase-IN-7 (Compound 6k) targets Aldose reductase. Aldose reductase-IN-7 exhibits potent enzyme inhibitory activity (Ki = 0.186 ± 0.020 μM), showing superiority to Epalrestat (HY-66009), which is currently in clinical use. Aldose reductase-IN-7 is less cytotoxic and possesses potent anticancer activity[1].

Formula: C21H20N4O7

References: [1]Güleç Ö,  et al. Novel spiroindoline derivatives targeting aldose reductase against diabetic complications: Bioactivity, cytotoxicity, and molecular modeling studies. Bioorg Chem. 2024 Apr;145:107221. 

Molecular Weight: 440.41

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Aldose Reductase

• SKU: MEXHY-161472-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161472-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK