Alpelisib, CAS 1217486-61-7

Description: Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity. Alpelisib inhibits PI3Kβ/γ/δ with low activity (IC50=250/290/1200 nM). Alpelisib has antitumor activity and is targeted to PIK3CA mutant tumors.

CAS Number: 1217486-61-7

Formula: C19H22F3N5O2S

Molecular Weight: 441,47

References: Gobin B, et al. BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma. Int J Cancer. 2015 Feb 15;136(4):784-96.

• SKU: TGMT1921-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T1921-5mg
• Package Unit: 5 mg
• Quantity Unit: STK