Product Description: Amikacin (Standard) is the analytical standard of Amikacin. This product is intended for research and analytical applications. Amikacin (BAY 41-6551), a semisynthetic analog of kanamycin, is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin (BAY 41-6551) is ototoxic and nephrotoxic[1][2].
Formula: N/A
References: [1]Farhan SM, et al. In Vitro and In Vivo Effect of Amikacin and Imipenem Combinations against Multidrug-Resistant E. coli. Trop Med Infect Dis. 2022 Oct 2;7(10):281. /[2]Wang YH, et al. Amikacin Suppresses Human Breast Cancer Cell MDA-MB-231 Migration and Invasion. Toxics. 2020 Nov 20;8(4):108. /[3]Atamer-Simsek S, et al. Antinociceptive effect of amikacin and its interaction with morphine and naloxone. Pharmacol Res. 2000 Mar;41(3):355-60. /[4]Ladrech S, et al. Calpain activity in the amikacin-damaged rat cochlea. J Comp Neurol. 2004 Sep 13;477(2):149-60. /[5]Chan K, et al. Characterization of Amikacin Drug Exposure and Nephrotoxicity in an Animal Model. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00859-20.
CAS Number: 37517-28-5
Molecular Weight: N/A
Research Area: Infection; Cancer
Target: Antibiotic;Bacterial
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