Product Description: Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication[1][2].
Applications: COVID-19-anti-virus
Formula: C48H75NO17
References: [1]Waheed AA, et al. Inhibition of human immunodeficiency virus type 1 assembly and release by the cholesterol-binding compound amphotericin B methyl ester: evidence for Vpu dependence. J Virol. 2008 Oct;82(19):9776-81./[2]Keim GR, et al. Comparative toxicological studies of amphotericin B methyl ester and amphotericin B in mice, rats, and dogs. ntimicrob Agents Chemother. 1976 Oct;10(4):687-90.
CAS Number: 36148-89-7
Molecular Weight: 938.11
Compound Purity: 81.0
Research Area: Infection
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Fungal;HIV
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