AMPte-Glu-γ-Glu, CAS 41600-13-9

AMPte-Glu-γ-Glu, CAS 41600-13-9
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MEXHY-122259-0
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MedChemExpress

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Product Description: AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity against chinese hamster ovaries cells, with IC50s of 20, 350 and 3 nM, for Pro3, R2, and 43-10, respectively[1].

Formula: C25H29N9O8

References: [1]Feng Y, et al., Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability. J Med Chem. 2006 Jan 26;49(2):770-88.

CAS Number: 41600-13-9

Molecular Weight: 583.55

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others
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SKU MEXHY-122259-0
Manufacturer MedChemExpress
Manufacturer SKU HY-122259-0
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