Androgen receptor-IN-6, CAS 3016437-05-8

Product Description: Androgen receptor-IN-6 (compound 16) is an orally available androgen receptor (Androgen Receptor) potent inhibitor (IC50=0.12 μM in vitro), targeting the disordered N-terminal domain (NTD). Androgen receptor-IN-6 has good Caco2 cell membrane permeability and has an oral activity (F/%) of 16% in male CD-1 mice[1].

Applications: Cancer-programmed cell death

Formula: C16H15N3OS

References: [1]Henry M C et al. Synthesis and evaluation of small molecule inhibitors of the androgen receptor N-terminal domain[J]. ACS Medicinal Chemistry Letters, 2023.

CAS Number: 3016437-05-8

Molecular Weight: 297.37

Compound Purity: 98.26

Research Area: cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Androgen Receptor

• SKU: MEXHY-155478-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155478-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK