Antibacterial agent 205

Product Description: Antibacterial agent 205 (Compound 10d) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-0.5 μg/mL. Antibacterial agent 205 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 205 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication[1].

Applications: COVID-19-immunoregulation

Formula: C32H30FN5O6

References: [1]Hu YG, et al., Discovery of indolylacryloyl-derived oxacins as novel potential broad-spectrum antibacterial candidates. Eur J Med Chem. 2024 Apr 15;270:116392.

Molecular Weight: 599.61

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Bacterial

• SKU: MEXHY-162429-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162429-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK