Antibiofilm agent-6

Product Description: Antibiofilm agent-6 (Compound 26c) is a quorum sensing inhibitor with strong antibiofilm effects that can inhibit the fluorescence intensity of PAO1-lasB-gfp and PAO1-pqsA-gfp in a concentration-dependent manner. Antibiofilm agent-6 can inhibit the production of pyocyanin and rhamnolipid. Antibiofilm agent-6 aids helps ciprofloxacin (HY-B0356) effectively eliminate the living bacteria in a mouse model infected with P. aeruginosa PAO1[1].

Formula: C15H12FN3O3

References: [1]Zhang P, et al. Design, Synthesis, and Biological Evaluation of 2-Phenoxyalkylhydrazide Benzoxazole Derivatives as Quorum Sensing Inhibitors with Strong Antibiofilm Effect. J Med Chem. 2024;67(7):5721-5743.

Molecular Weight: 301.27

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Bacterial

• SKU: MEXHY-163481-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163481-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK