Product Description: Antiparasitic agent-22 (Compound 24) is a pan antiparasitic agent, that inhibits T. Brucei, L. infantum, L. tropica promastigotes (IC50 of 2.41, 5.95, 8.98 μM), L. infantum amastigotes (IC50 of 8.18 μM) and P. falciparum W2 strain (IC50 of 0.155 μM). Antiparasitic agent-22 exhibits low cytotoxicity against THP1, with CC50 of 64.16 μM[1].
Applications: COVID-19-immunoregulation
Formula: C18H20BrN3O3
References: [1]Corfu AI, et al., Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents. ACS Infect Dis. 2024 May 8.
Molecular Weight: 406.27
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Parasite