Product Description: Antitumor agent-149 (Compound 3) is an analogue of Echinomycin (HY-106101). Antitumor agent-149 inhibits HIF-1α-mediated transcription. Antitumor agent-149 induces cancer cell apoptosis. Antitumor agent-149 inhibits tumor growth in SW620 xenograft mice model[1].
Formula: C52H64N10O14S
References: [1]Kojima K, et al. Synthesis and biological evaluation of echinomycin analogues as potential colon cancer agent. Sci Rep. 2024 Apr 1;14(1):7628.