Apcin-A (monohydrochloride), CAS 1683535-53-6

Product Description: Apcin-A monohydrochloride, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A monohydrochloride interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A monohydrochloride can be used to synthesize the PROTAC CP5V (HY-130257)[1].

Applications: Cancer-programmed cell death

Formula: C10H15Cl4N5O2

References: [1] Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

CAS Number: 1683535-53-6

Molecular Weight: 379.07

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: APC;Ligands for Target Protein for PROTAC

• SKU: MEXHY-W614725-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W614725-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK