AR antagonist 8

Product Description: AR antagonist 8 (compound 16) is a potent Lupeol-inspired androgen receptor (AR) antagonist with an IC50 of 0.76 μM. AR antagonist 8 is a uniquely substituted unnatural entestrane[1].

Formula: C22H32O

References: [1]Zachary D Stempel, et al. Function-Oriented Synthesis of Pentacyclic Triterpenoids and Discovery of an ent-Estrane as a Natural Product-Inspired Androgen Receptor Antagonist. Org Lett. 2024 Apr 19;26(15):3054-3059.

Molecular Weight: 312.49

Research Area: Endocrinology

Solubility: 10 mM in DMSO

Target: Androgen Receptor

• SKU: MEXHY-163485-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163485-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK