AR/AR-V7-IN-1, CAS 2964558-54-9

Product Description: AR/AR-V7-IN-1 (Compound 20i) is an AR/ARV7 inhibitor (IC50 = 172.85 nM). AR/AR-V7-IN-1 potently inhibits cell growth with IC50 values of 4.87 and 2.07 μM in the LNCaP and 22RV1 cell lines, respectively. AR/AR-V7-IN-1 exhibits effective tumor growth inhibition in the 22RV1 xenograft study. AR/AR-V7-IN-1 can be used for the research of prostate cancer[1].

Formula: C36H43ClFN7O2

References: [1]Yang Y, et al. Novel selective agents for the degradation of AR/AR-V7 to treat advanced prostate cancer. Eur J Med Chem. 2024 Apr 15;271:116400.

CAS Number: 2964558-54-9

Molecular Weight: 660.22

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Androgen Receptor

• SKU: MEXHY-163510-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163510-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK