ATR kinase substrate peptide

Product Description: ATR kinase substrate peptide (compound 45) is a potent and selective inhibitor of ATR (Ataxia Telangiectasia and Rad3 related) protein kinase (Ki=6 nM). ATR kinase substrate peptide inhibits ATR activity by competing with ATR kinase ATP-binding sites to block ATR mediated signaling. ATR kinase substrate peptide can be used to study the role of ATR kinase in DNA damage response[1].

Applications: Cancer-Kinase/protease

Formula: C81H132N22O25

References: [1]Charrier J D, et al. Discovery of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents[J]. Journal of medicinal chemistry, 2011, 54(7): 2320-2330.

Molecular Weight: 1814.05

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ATM/ATR

• SKU: MEXHY-P10280-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10280-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK