Product Description: AU-24118 is orally bioavailable proteolysis targeting chimera (PROTAC) degrader of mSWI/SNF ATPases (SMARCA2 and SMARCA4) and PBRM1[1].
Formula: C37H40N6O4
References: [1]Tongchen He, et al. Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. bioRxiv [Preprint]. 2024 Mar 2:2024.02.29.582768.