AZ-4217, CAS 1383846-83-0

Product Description: AZ-4217 is an inhibitor for β-site amyloid precursor protein cleavage enzyme 1 (BACE1), with IC50 of 160 pM in human SH-SY5Y cells. AZ-4217 reduces amyloid deposition in Tg2576 mouse models, and is used for Alzheimer’s Disease research[1].

Formula: C30H25FN4O

References: [1]Eketjäll S, et al., AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. J Neurosci. 2013 Jun 12;33(24):10075-84.

CAS Number: 1383846-83-0

Molecular Weight: 476.54

Research Area: Neurological Disease

Target: Beta-secretase

• SKU: MEXHY-18112-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18112-0
• Package Unit: Get quote
• Quantity Unit: STK