AZD-5991 (S-enantiomer), CAS 2143061-82-7

Product Description: AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

Applications: Cancer-programmed cell death

Formula: C35H34ClN5O3S2

References: [1]Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.

CAS Number: 2143061-82-7

Molecular Weight: 672.26

Compound Purity: 99.83

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Bcl-2 Family

• SKU: MEXHY-101533B-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101533B-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK