Azide-PEG8-Val-Cit-PAB-MMAE

Products from BPS Bioscience require a minimum order value above 400€

Description: Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient MMAE payload delivery via an elimination mechanism within the PAB structure.

Format: Solid

Purity: 0,98

Storage Stability: At least 6 months at -20°C. 

Warnings: Avoid freeze/thaw cycles. See SDS for additional warnings and handling.

Biosafety Level: Not applicable (BSL-1)

• SKU: BPS82277-3
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 82277-3
• Package Unit: 10 mg
• Quantity Unit: STK