Azumolene (sodium), CAS 105336-14-9

Azumolene (sodium), CAS 105336-14-9
SKU
MEXHY-113920-0
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MedChemExpress

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Product Description: Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca2+ homeostasis failure caused by Halothane (HY-B1010)/Succinylcholine. Azumolene sodium (0.5-2.0 mg/kg) reduces [Ca2+]i (from 207 nM to 38 nM) in MH-susceptible skeletal muscle following intramuscular injection[1].

Applications: Neuroscience-Neuromodulation

Formula: C13H9BrN4NaO3

References: [1]Allen P D, Lopez J R, Sanchez V, et al. EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine[J]. Anesthesiology, 1992, 76(1): 132-138.

CAS Number: 105336-14-9

Molecular Weight: 372.13

Research Area: Others

Solubility: 10 mM in DMSO

Target: Calcium Channel
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SKU MEXHY-113920-0
Manufacturer MedChemExpress
Manufacturer SKU HY-113920-0
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