Product Description: BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261)[1].
Applications: COVID-19-anti-virus
Formula: C22H25N3O4S
References: [1]McSharry JJ, et al., Susceptibilities of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir. Antimicrob Agents Chemother. 2001 Oct;45(10):2925-7.
CAS Number: 233255-39-5
Molecular Weight: 427.52
Research Area: Infection
Solubility: 10 mM in DMSO
Target: CMV