BAY-707, CAS 2109805-96-9

Product Description: BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy[1].

Applications: Cancer-programmed cell death

Formula: C15H20N4O2

References: [1]Ellermann M, et al. Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.ACS Chem Biol. 2017 Aug 18;12(8):1986-1992.

CAS Number: 2109805-96-9

Molecular Weight: 288.34

Compound Purity: 99.64

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: DNA/RNA Synthesis

• SKU: MEXHY-112081-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112081-10.1
• Green Labware: No
• Package Unit: 10mM/1mL
• Quantity Unit: STK