BCL-xL/BCL-2 ligand 1, CAS 2941091-91-2

Product Description: BCL-xL/BCL-2 ligand 1 (compound 72-1) is a BCL-xL and BCL-2 protein ligand. BCL-xL/BCL-2 ligand 1 can be connected to the E3 ligase by a linker to form PROTACs (HY-161410)[1][2].

Formula: C48H53ClF3N5O7S3

References: [1]Guangrong Zheng, et al. Bcl-xl/bcl-2 dual degraders for treatment of cancers. WO2023107606A1./[2]Nayak D, et al. Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun. 2024 Mar 29;15(1):2743.

CAS Number: 2941091-91-2

Molecular Weight: 1000.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Ligands for E3 Ligase

• SKU: MEXHY-161415-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161415-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK