Product Description: BDM19 binds and activates cytosolic BAX dimers, and prompts cell apoptosis either alone or in combination with BCL-2/BCL-XL inhibitor Navitoclax (HY-10087)[1].
Applications: Cancer-programmed cell death
Formula: C24H17IN2O3
References: [1]Gitego N, et al. Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nat Commun. 2023;14(1):8381. Published 2023 Dec 16.