Product Description: Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C7H7NO
References: [1]Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996 Oct 7;735(2):343-8.
CAS Number: 55-21-0
Molecular Weight: 121.14
Compound Purity: 99.85
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Endogenous Metabolite;PARP
English
Deutsch
