BET-IN-19, CAS 1643947-30-1

Product Description: BET-IN-19 (Compound 146) is a BET inhibitor. BET-IN-19 inhibits hlL-6 mRNA transcription (IC50 ≤ 0.3 uM), and c-myc activity in human AML MV4-11 cell (IC50 ≤ 0.3 uM)。BET-IN-19 inhibits tetra-acetylated histone H4 binding to BRD4 bromodomain 1 (IC50 ≤ 0.3 uM)[1].

Formula: C19H19N5O

References: [1]Bryan Cordell DUFFY, et al. Novel bicyclic bromodomain inhibitors. Patent. WO2015002754 A2.

CAS Number: 1643947-30-1

Molecular Weight: 333.39

Compound Purity: 99.41

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain

• SKU: MEXHY-125236-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125236-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK