Biotin-PEG6-azide, CAS 1085938-09-5

Product Description: Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C24H44N6O8S

References: [1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

CAS Number: 1085938-09-5

Molecular Weight: 576.71

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: PROTAC Linkers

• SKU: MEXHY-140911-250
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-140911-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK