BTT-266

Product Description: BTT-266 is an antagonist forcalcium channel, through suppression of the CaVα1-AID-CaVβ3 interaction, with a Ki of 1.4 μM. BTT-266 modulates the activation of voltage-dependent CaV2.2. BTT-266 exhibits analgesic efficacy against neuropathic pain in rats model[1].

Applications: Neuroscience-Neuromodulation

Formula: C34H28N4O4

References: [1]Chen X, et al., Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10566-E10575.

Molecular Weight: 556.61

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Calcium Channel

• SKU: MEXHY-115597-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-115597-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK