BWA-522 intermediate-1, CAS 2241315-66-0

Product Description: BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7[1].

Applications: Cancer-programmed cell death

Formula: C19H19N3O5

References: [1]Arvinas Operations, et al. Indazole based compounds and associated methods of use. World Intellectual Property Organization, WO2021194879 A1 2021-09-30.

CAS Number: 2241315-66-0

Molecular Weight: 369.37

Compound Purity: 99.27

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Ligands for E3 Ligase

• SKU: MEXHY-W877989-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W877989-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK