Product Description: C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) is a specific type of long-chain molecule found in murine skin[1]. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) promotes migration of both mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells at concentrations between 0.5-5 µM. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt)’s levels are higher in CFPAC-1 pancreatic ductal adenocarcinoma cells than in pancreatic cancer stem cells[2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C36H75N2O6P
References: [1]Yamashita, R., et al. Analysis of molecular species profiles of ceramide-1-phosphate and sphingomyelin using MALDI-TOF mass spectrometry Lipids 51(2),263-270 (2016)./[2]Kuc, N., et al. Pancreatic ductal adenocarcinoma cell secreted extracellular vesicles containing ceramide-1-phosphate promote pancreatic cancer stem cell motility Biochem. Pharmacol. 156,458-466 (2018).
CAS Number: 384835-48-7
Molecular Weight: 662.96
Research Area: Endocrinology
Solubility: 10 mM in DMSO
Target: Others