Cabozantinib, CAS 849217-68-1

Description: Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity.

CAS Number: 849217-68-1

Formula: C28H24FN3O5

Molecular Weight: 501,51

References: Dai J, et al. Cabozantinib inhibits prostate cancer growth and prevents tumor-induced bone lesions. Clin Cancer Res. 2014 Feb 1;20(3):617-30.

• SKU: TGMT2586-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T2586-1mL
• Package Unit: 1 mL
• Quantity Unit: STK