Calyculin A, CAS 101932-71-2

Calyculin A, CAS 101932-71-2
SKU
MEXHY-18983-5UG
Packaging Unit
5 μg (0.5 mM * 10 μL in DMSO)
Manufacturer
MedChemExpress

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Product Description: Calyculin A ((-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 2 nM and 0.5-1 nM, respectively[1].

Applications: Cancer-programmed cell death

Formula: C50H81N4O15P

References: [1]Ishihara H, et al. Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem Biophys Res Commun. 1989 Mar 31;159(3):871-7./[2]Hiroaki Tanaka,et al. Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-kappaB in human osteoblastic osteosarcoma MG63 cells. Int J Oncol. 2007 Aug;31(2):389-96.

CAS Number: 101932-71-2

Molecular Weight: 1009.17

Compound Purity: 99.67

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Phosphatase
More Information
SKU MEXHY-18983-5UG
Manufacturer MedChemExpress
Manufacturer SKU HY-18983-5UG
Green Labware No
Package Unit 5 μg (0.5 mM * 10 μL in DMSO)
Quantity Unit STK
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