Cap-dependent endonuclease-IN-28

Product Description: Cap-dependent endonuclease-IN-28 (Compound 11) is a potent cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-28 inhibits CEN of TOSV, ANDV, and LACV viruses with IC50 values ​​of 2.4, 0.5, and 4 μM, respectively[1].

Formula: C15H13NO5

References: [1]Miglioli F, et al. Inhibitory interactions of the 2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-one scaffold with Bunyavirales cap-snatching endonucleases expose relevant drug design features. Eur J Med Chem. 2024 Jun 5;272:116467.

Molecular Weight: 287.27

Research Area: Infection

Target: Influenza Virus

• SKU: MEXHY-163621-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163621-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK