CARM1-IN-5

Product Description: CARM1-IN-5 (Compound 17e) is a potent and selective inhibitor of CARM1 (IC50= 2 nM). CARM1-IN-5 effectively prevents CARM1 from methylating substrate proteins by directly interacting with CARM1. CARM1-IN-5 exhibits significant antiproliferative effects on melanoma cell lines[1].

Applications: Cancer-programmed cell death

Formula: C22H26ClN3O2S

References: [1]Liu Z, et al. Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma. J Med Chem. 2024 Apr 25;67(8):6313-6326.

Molecular Weight: 431.98

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Histone Methyltransferase

• SKU: MEXHY-158158-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158158-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK