Product Description: Cbl-b-IN-18 (compound 51) is an inhibitor of the E3 ligase Casitas B-lineage lymphoma proto-oncogene B (CPL-B). Cbl-b-IN-18 inhibits the phosphorylation of CPL-B (IC50[1].
Formula: C33H31F4N7O
References: [1]Murugan CHINNAPATTU, et al. Bicyclic heterocyclic compounds as cbl-b inhibitors. Worldwide, WO2024062363A1. 2023-09-18