CBP/p300 ligand 4

Product Description: CBP/p300 ligand 4 (Compound 4) is an orally active inhibitor for CBP/p300 bromodomain, with IC50 of 91.4 nM. CBP/p300 ligand 4 serves as a ligand for target protein XYD190 (HY-161495). XYD190 is a PROTAC degrader for CBP/p300[1].

Applications: Cancer-programmed cell death

Formula: C30H31F2N5O4

References: [1]Hu J, et al., Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity. J Med Chem. 2024 May 9;67(9):6952-6986. 

Molecular Weight: 563.60

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Epigenetic Reader Domain;Ligands for Target Protein for PROTAC

• SKU: MEXHY-161495-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161495-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK