Product Description: Cdc7-IN-21 (compound 10c) is a potent and selective Cdc7 inhibitor with an IC50 of 0.07 nM. Cdc7-IN-21 can be used to study cancer[1].
Applications: Cancer-Kinase/protease
Formula: C15H17N5OS
References: [1]Kurasawa O, et al. 2-Aminomethylthieno [3, 2-d] pyrimidin-4 (3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase[J]. Bioorganic & Medicinal Chemistry, 2017, 25(14): 3658-3670.
CAS Number: 1330781-04-8
Molecular Weight: 315.39
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: CDK